01.08 Cardio

01.08 Cardiology [PDF link]: Deep vein thrombosis (DVT) – Well’s score + anticoagulation. Pulmonary embolism (PE) – Well’s score, PERC score. Infective endocarditis – HACEK organisms. Pericarditis – pericardial rub, Dressler’s syndrome. Constructive pericarditis.

External links

• Well’s score for DVT: MDCalc

• Well’s score for PE: MDCalc

• PERC score for PE: MDCalc

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Doses for DVT/PE treatment & prophylaxis [per BNF]

• Apixaban

  • Treatment dose: 10 mg BDS for 7 days (loading dose), followed by maintenance 5 mg BDS

  • Prophylactic dose (prevention of recurrent DVT/PE or post knee/hip replacement): 2.5 mg BDS, following completion of 6 months anticoagulant treatment.

• Rivaroxaban

  • Treatment dose: 15 mg BDS for 21 days, then maintenance 20 mg OD

  • Prophylactic dose (prevention of recurrent DVT/PE): 10 mg OD

  • See BNF for other indications/doses

• Enoxaparin (LMWH)

  • Treatment dose for uncomplicated patients: 1.5 mg/kg OD

  • Treatment dose in complicated pts (eg obese, cancer, etc): 1 mg/kg BDS

  • See BNF for other indications/doses